- Diabetes Genes
- What is Maturity-Onset Diabetes of the Young?
- Hepatic Nuclear Factor 1 Alpha (HNF1A)
Hepatic Nuclear Factor 1 Alpha (HNF1A)
HNF1A is a gene which acts as a switch that turns on and off other genes in the body. Changes in the HNF1A gene cause diabetes by lowering the amount of insulin that is produced by the pancreas. It allows insulin to be produced normally in childhood but the amount of insulin reduces as you get older. HNF1A is the commonest cause of monogenic diabetes in the UK and accounts for approximately 50% of cases.
What can we say about diabetes caused by changes in HNF1A?
How is HNF1A diabetes treated?
Does this result mean that my diabetes is the same as my parent who had diabetes?
How does this affect other family members?
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