Diabetes Genes


Lead Site, CI

Study Team & Contact Details

Chief Investigator
Professor Andrew Hattersley

University of Exeter, and Royal Devon University Healthcare NHS Foundation Trust

Study Team
Catherine Angwin
Caroline Jenkinson
Claire Thorne
Nina Rickards

01392 408180

Exeter CRF Team
01392 408181

Study Refs

REC: SC/16/0147

IRAS:  83044

MHRA: 2015-002790-38

ClinicalTrials.gov: NCT02653209


Funder: Medical Research Council (MRC) MR/N00633X/1

A research study to help improve treatment of type 2 diabetes, by learning how individuals respond to different blood sugar-lowering drugs

Inclusion criteria

  1. Clinical diagnosis of Type 2 diabetes
  2. Age ≥30 and ≤80
  3. Currently treated with either metformin alone or two classes of oral glucose-lowering therapy (given either as separate or combined medications), that do not include a DPP4-inhibitor, a SGLT2-inhibitor or a thiazolidinedione.
  4. Diabetes duration ≥ 12 months
  5. No change in diabetes treatment (new treatments or dose change) within previous 3 months
  6. HbA1c > 58mmol/mol (7.5%) and ≤110mmol/mol (12.2%)
  7. eGFR ≥ 60mls/min/1.73m²
  8. Able and willing to give informed consent


Privacy, Terms and Cookies