Diabetes Genes


Lead Site, CI

Study Team & Contact Details

Chief Investigator
Professor Andrew Hattersley

University of Exeter, and Royal Devon and Exeter NHS Foundation Trust

Trial Manager
Catherine Angwin 01392 408185

Study Team
Caroline Jenkinson 01392 408179
Claire Thorne 01392 408180
Nina Rickards 01392 408186

Lead Nurse
Kim Rowden 01392 408181

Study Refs

REC: SC/16/0147

IRAS:  83044

MHRA: 2015-002790-38

ClinicalTrials.gov: NCT02653209


Funder: Medical Research Council (MRC) MR/N00633X/1

A research study to help improve treatment of type 2 diabetes, by learning how individuals respond to different blood sugar-lowering drugs

Inclusion criteria

  1. Clinical diagnosis of Type 2 diabetes
  2. Age ≥30 and ≤80
  3. Currently treated with either metformin alone or two classes of oral glucose-lowering therapy (given either as separate or combined medications), that do not include a DPP4-inhibitor, a SGLT2-inhibitor or a thiazolidinedione.
  4. Diabetes duration ≥ 12 months
  5. No change in diabetes treatment (new treatments or dose change) within previous 3 months
  6. HbA1c > 58mmol/mol (7.5%) and ≤110mmol/mol (12.2%)
  7. eGFR ≥ 60mls/min/1.73m²
  8. Able and willing to give informed consent