Diabetes Genes

DROPLET

For Patients Interested In Taking Part:

Please Download The Information Leaflet

DROPLeT Participant Information Leaflet

 

OR

Contact The Study Team To Discuss Taking Part

Inclusion criteria

  1. Clinical diagnosis of type 1 diabetes within the last 100 days
  2. Aged 18 or over at the time of diagnosis
  3. Currently treated with Insulin
  4. Able and willing to give informed consent
  5. A resident of England, Scotland or Wales

Defining the Rate Of Progression of Late onset Type 1 diabetes

Type 1 diabetes is associated with loss of insulin release, which results in high blood sugars. In children and young adults this loss of insulin is known to happen quickly. After just a couple of years of having type 1 diabetes, most of this age group will make almost no insulin. Research is trying to find new treatments to slow down and even stop this insulin loss. Those developing type 1 diabetes after 30 years of age are rarely included in these trials- despite making up nearly half of all cases of type 1 diabetes. This is because, in this age group, the rate of insulin loss is unknown. Finding out this rate and factors that effect it is an important step towards including older individuals in trials.

We are also testing a new, simpler way of monitoring insulin loss by using a finger prick blood test, making it possible to conduct research from home rather than in hospital or a research clinic. Together, the answers to these questions aim to make it easier to develop new treatments for type 1 diabetes, as these studies could recruit many more people, using a much simpler and cheaper measure of insulin loss.

The study will recruit 196 adults aged 18 and over within 100 days of a clinical diagnosis of type 1 diabetes. We will compare the loss of insulin production of 135 participants diagnosed >30 years of age with 61 participants diagnosed  18 to 30 years of age.

All study procedures are carried out at home, with phone or video support from the research team.  Study packs are delivered and collected by courier or tracked mail.

We welcome referrals and expressions of interest from all parts of England, Scotland & Wales.

 

 

Lead Site & Contact Details

Study Team

Lead Site: Exeter

Chief Investigator: Dr Angus Jones

Co Investigator: Dr Nick Thomas

Central Coordinating Team:

Anita Hill (Project Manager)

Peter Tippett (Administrator)

Contact:

rde-tr.diabetesresearch@nhs.net

Phone: 01392 408184

ClinicalTrials.gov Identifier: NCT04682457

Supported by funding from: